Mitochondrial Dna Depletion Syndrome 6 (MTDPS6)

Mitochondrial Dna Depletion Syndrome 6, also known as navajo neurohepatopathy, is related to lactic acidosis and mitochondrial dna depletion syndrome 3, and has symptoms including ataxia, diarrhea and vomiting. An important gene associated with Mitochondrial Dna Depletion Syndrome 6 is MPV17 (Mitochondrial Inner Membrane Protein MPV17), and among its related pathways/superpathways are Pyrimidine metabolism and related diseases and Valproic Acid Pathway, Pharmacodynamics. Affiliated tissues include liver and eye, and related phenotypes are decreased activity of mitochondrial complex i and decreased number of peripheral myelinated nerve fibers