Mismatch Repair Cancer Syndrome (BTPS1)

Alias:

Turcot Syndrome

Constitutional Mismatch Repair Deficiency Syndrome

Brain Tumor-Polyposis Syndrome 1

Malignant Childhood Neoplasm

Childhood Cancer Syndrome

Cmmr-D Syndrome

Mmr Deficiency

Btp1 Syndrome

Cmmrds

Btps1

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Mismatch Repair Cancer Syndrome, also known as turcot syndrome, is related to mismatch repair cancer syndrome 1 and neurofibromatosis, type i. An important gene associated with Mismatch Repair Cancer Syndrome is MSH6 (MutS Homolog 6), and among its related pathways/superpathways are Infectious disease and Cell Cycle, Mitotic. The drugs Cyclophosphamide and Thalidomide have been mentioned in the context of this disorder. Affiliated tissues include brain and colon, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Decreased viability

Related ID：

MALACARDS：MSM014