Menkes Disease (MNK)

Menkes Disease, also known as menkes syndrome, is related to occipital horn syndrome and disorder of copper metabolism, and has symptoms including seizures An important gene associated with Menkes Disease is ATP7A (ATPase Copper Transporting Alpha), and among its related pathways/superpathways are Detoxification of Reactive Oxygen Species and Copper homeostasis. The drugs Histidine and Copper have been mentioned in the context of this disorder. Affiliated tissues include skin and brain, and related phenotypes are seizure and spasticity