Multiple Sulfatase Deficiency (MSD)

Multiple Sulfatase Deficiency, also known as mucosulfatidosis, is related to leukodystrophy and ichthyosis, x-linked, and has symptoms including ataxia and muscle spasticity. An important gene associated with Multiple Sulfatase Deficiency is SUMF1 (Sulfatase Modifying Factor 1), and among its related pathways/superpathways are Metabolism of proteins and Metabolism. The drug Coal tar has been mentioned in the context of this disorder. Affiliated tissues include skin and eye, and related phenotypes are intellectual disability and developmental regression