Multicentric Castleman Disease, also known as multi-centric castleman's disease, is related to kaposi sarcoma and polyclonal hypergammaglobulinemia, and has symptoms including fever An important gene associated with Multicentric Castleman Disease is VIL1 (Villin 1), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Thalidomide and Valganciclovir have been mentioned in the context of this disorder. Affiliated tissues include lymph node and spleen, and related phenotypes are homeostasis/metabolism and growth/size/body region