Multiple Carboxylase Deficiency (MCD)

Multiple Carboxylase Deficiency, also known as mcd, is related to holocarboxylase synthetase deficiency and metabolic acidosis, and has symptoms including exanthema, lethargy and seizures. An important gene associated with Multiple Carboxylase Deficiency is HLCS (Holocarboxylase Synthetase), and among its related pathways/superpathways are Metabolism and Regulation of expression of SLITs and ROBOs. Affiliated tissues include skin and spinal cord, and related phenotypes are Increased shRNA abundance (Z-score > 2) and renal/urinary system