Melanoma, Cutaneous Malignant 8 (CMM8)

Melanoma, Cutaneous Malignant 8, also known as melanoma, cutaneous malignant, susceptibility to, 8, is related to nodular malignant melanoma and ocular melanoma. An important gene associated with Melanoma, Cutaneous Malignant 8 is MITF (Melanocyte Inducing Transcription Factor), and among its related pathways/superpathways is GPR143 in melanocytes and retinal pigment epithelium cells. The drugs Aldesleukin and Nivolumab have been mentioned in the context of this disorder. Affiliated tissues include skin and lung, and related phenotypes are cutaneous melanoma and pigmentation