Melkersson-Rosenthal Syndrome, also known as melkersson syndrome, is related to fissured tongue and facial paralysis, and has symptoms including oral manifestations and lip swelling. An important gene associated with Melkersson-Rosenthal Syndrome is MROS (Melkersson-Rosenthal Syndrome), and among its related pathways/superpathways are ACE Inhibitor Pathway, Pharmacodynamics and Dravet syndrome. Affiliated tissues include tongue and skin, and related phenotypes are cranial nerve paralysis and mask-like facies