Malignant Hyperthermia 1, also known as malignant hyperthermia, susceptibility to, 1, is related to congenital myopathy 1a and malignant hyperthermia susceptibility, and has symptoms including fever, muscle rigidity and pain, postoperative. An important gene associated with Malignant Hyperthermia 1 is RYR1 (Ryanodine Receptor 1), and among its related pathways/superpathways are Myometrial relaxation and contraction pathways and Ion channel transport. Affiliated tissues include skeletal muscle and heart, and related phenotypes are fever and malignant hyperthermia