Malignant Peripheral Nerve Sheath Tumor (MPNST)

Alias:
Malignant Neurilemmoma
Neurofibrosarcoma
Mpnst
Malignant Neurofibroma
Malignant Schwannoma
Neurogenic Sarcoma
Malignant Neoplasm of the Peripheral Nerve Sheath
Malignant Peripheral Nerve Sheath Tumors
Schwannoma, Malignant
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Malignant Peripheral Nerve Sheath Tumor, also known as malignant neurilemmoma, is related to malignant triton tumor and epithelioid malignant peripheral nerve sheath tumor. An important gene associated with Malignant Peripheral Nerve Sheath Tumor is NF1 (Neurofibromin 1), and among its related pathways/superpathways are Infectious disease and Apoptotic Pathways in Synovial Fibroblasts. The drugs Mechlorethamine and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include lung and t cells, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Decreased viability
Related ID:
MESH:D018319

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
Infant
1-9/100000
34
774
--

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

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CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
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IF
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