Malignant Peripheral Nerve Sheath Tumor (MPNST)

Malignant Peripheral Nerve Sheath Tumor(来自ICD-11)
别称:
Malignant Neurilemmoma
Neurofibrosarcoma
Mpnst
Malignant Neurofibroma
Malignant Schwannoma
Neurogenic Sarcoma
Malignant Neoplasm of the Peripheral Nerve Sheath
Malignant Peripheral Nerve Sheath Tumors
Schwannoma, Malignant
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Malignant Peripheral Nerve Sheath Tumor, also known as malignant neurilemmoma, is related to malignant triton tumor and epithelioid malignant peripheral nerve sheath tumor. An important gene associated with Malignant Peripheral Nerve Sheath Tumor is NF1 (Neurofibromin 1), and among its related pathways/superpathways are Infectious disease and Apoptotic Pathways in Synovial Fibroblasts. The drugs Mechlorethamine and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include lung and t cells, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Decreased viability
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相关ID:
MESH:D018319

基础信息

遗传方式
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参考文献
MALACARDS
--
Infant
1-9/100000
34
774
--

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靶点药物

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MGI
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