Malignant Giant Cell Tumor of Soft Parts, also known as malignant giant cell neoplasm of soft parts, is related to malignant giant cell tumor and bone giant cell tumor. An important gene associated with Malignant Giant Cell Tumor of Soft Parts is LHFPL6 (LHFPL Tetraspan Subfamily Member 6). Affiliated tissues include skin, and related phenotype is Synthetic lethal with vaccinia virus (VACV) infection.