Malignant Spindle Cell Melanoma

Alias:
Spindle Cell Melanoma
Desmoplastic Melanoma
Spindle Cell Malignant Melanoma
Spitzoid Malignant Melanoma
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Malignant Spindle Cell Melanoma, also known as spindle cell melanoma, is related to spindle cell intraocular melanoma and malignant choroid melanoma. An important gene associated with Malignant Spindle Cell Melanoma is SOX10 (SRY-Box Transcription Factor 10), and among its related pathways/superpathways are Signal Transduction and Prolactin Signaling. The drugs Pembrolizumab and Immune Checkpoint Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include lymph node and skin, and related phenotypes are pigmentation and homeostasis/metabolism
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Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Unknown
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20
555
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Medical Symptom

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Gene & Mutation

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Disease Model

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MGI
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References Literature

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