Major Affective Disorder 1, also known as bipolar affective disorder, is related to neurotic disorder and bipolar i disorder. An important gene associated with Major Affective Disorder 1 is MAFD1 (Major Affective Disorder 1), and among its related pathways/superpathways are Sudden infant death syndrome (SIDS) susceptibility pathways and Monoamine transport. The drugs Asenapine and Risperidone have been mentioned in the context of this disorder. Affiliated tissues include brain and prefrontal cortex, and related phenotypes are depression and mania