Migraine with or Without Aura 1, also known as migraine, is related to familial hemiplegic migraine and migraine without aura, and has symptoms including back pain, headache and hemiplegia. An important gene associated with Migraine with or Without Aura 1 is NOTCH3 (Notch Receptor 3), and among its related pathways/superpathways are Disturbed pathways in Duchenne Muscular Dystrophy and Type II diabetes mellitus. The drugs Mineral oil and Betamethasone have been mentioned in the context of this disorder. Affiliated tissues include brain and spinal cord, and related phenotypes are photophobia and vomiting