Migraine with Aura, also known as migraine with typical aura, is related to migraine, familial hemiplegic, 1 and familial or sporadic hemiplegic migraine, and has symptoms including headache An important gene associated with Migraine with Aura is NOTCH3 (Notch Receptor 3), and among its related pathways/superpathways are Monoamine GPCRs and Serotonin HTR1 group and FOS pathway. The drugs Milnacipran and Norepinephrine have been mentioned in the context of this disorder. Affiliated tissues include brain and endothelial, and related phenotypes are nervous system and growth/size/body region