Megalencephalic Leukoencephalopathy with Subcortical Cysts (LVM)

Megalencephalic Leukoencephalopathy with Subcortical Cysts, also known as vacuolating megalencephalic leukoencephalopathy with subcortical cysts, is related to megalencephalic leukoencephalopathy with subcortical cysts 2a and megalencephalic leukoencephalopathy with subcortical cysts 1, and has symptoms including ataxia, muscle spasticity and seizures. An important gene associated with Megalencephalic Leukoencephalopathy with Subcortical Cysts is MLC1 (Modulator Of VRAC Current 1), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Neuroinflammation and glutamatergic signaling. Affiliated tissues include brain and cortex, and related phenotypes are homeostasis/metabolism and nervous system