Microvascular Complications of Diabetes 1, also known as proliferative diabetic retinopathy, is related to background diabetic retinopathy and macular holes, and has symptoms including neuralgia and sciatica. An important gene associated with Microvascular Complications of Diabetes 1 is VEGFA (Vascular Endothelial Growth Factor A), and among its related pathways/superpathways are Innate Immune System and Apoptotic Pathways in Synovial Fibroblasts. The drugs Vildagliptin and Clopidogrel have been mentioned in the context of this disorder. Affiliated tissues include retina and kidney, and related phenotypes are homeostasis/metabolism and nervous system