Microtia

Microtia, also known as congenital small ears, is related to meier-gorlin syndrome 1 and mandibulofacial dysostosis, guion-almeida type. An important gene associated with Microtia is KMT2D (Lysine Methyltransferase 2D), and among its related pathways/superpathways are RNA Polymerase I Promoter Opening and Cell Cycle, Mitotic. The drugs Racepinephrine and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include eye and bone, and related phenotypes are microtia and delayed speech and language development