Mucopolysaccharidosis-Plus Syndrome (MPSPS)

Mucopolysaccharidosis-Plus Syndrome, also known as mucopolysaccharidosis, is related to hurler-scheie syndrome and hurler syndrome. An important gene associated with Mucopolysaccharidosis-Plus Syndrome is VPS33A (VPS33A Core Subunit Of CORVET And HOPS Complexes), and among its related pathways/superpathways are Infectious disease and Innate Immune System. The drugs Rituximab and Methotrexate have been mentioned in the context of this disorder. Affiliated tissues include heart and bone, and related phenotypes are coarse facial features and global developmental delay