Muckle-Wells Syndrome (MWS)

Muckle-Wells Syndrome, also known as neutrophilic urticaria, is related to cryopyrin-associated periodic syndrome and familial cold autoinflammatory syndrome 1, and has symptoms including lower extremity pain An important gene associated with Muckle-Wells Syndrome is NLRP3 (NLR Family Pyrin Domain Containing 3), and among its related pathways/superpathways are Infectious disease and Innate Immune System. The drugs Ginseng and Calcium polycarbophil have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are splenomegaly and hepatomegaly