Lynch Syndrome 1 (LYNCH1)

Alias:

Colorectal Cancer, Hereditary Nonpolyposis, Type 1

Hnpcc1

Lynch1

Fcc1

Cancer, Colorectal, Nonpolyposis, Hereditary, Type 1

Colorectal Cancer, Hereditary Nonpolyposis, Type 3

Hereditary Nonpolyposis Colorectal Cancer Type 1

Hereditary Non-Polyposis Colorectal Cancer 1

Hereditary Non-Polyposis Colon Cancer Type 2

Colon Cancer, Familial Nonpolyposis, Type 1

Familial Nonpolyposis Colon Cancer Type 1

Hereditary Nonpolyposis Colorectal Cancer

Lynch Cancer Family Syndrome

Lynch Syndrome Ii, Formerly

Lynch Syndrome I, Formerly

Lynch Syndrome Type Ii

Lynch Syndrome Type I

Lynch Syndrome I

Lynch Syndrome

Coca1

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Lynch Syndrome 1, also known as colorectal cancer, hereditary nonpolyposis, type 1, is related to lynch syndrome 4 and lynch syndrome 5. An important gene associated with Lynch Syndrome 1 is MSH2 (MutS Homolog 2), and among its related pathways/superpathways are Homology Directed Repair and Regulation of TP53 Activity. The drugs Fluorouracil and Oxaliplatin have been mentioned in the context of this disorder. Affiliated tissues include colon and small intestine, and related phenotypes are colon cancer and Synthetic lethal with MLN4924 (a NAE inhibitor)

Related ID：

MALACARDS：LYN005

OMIM：120435

MESH：D003123