Lymphoproliferative Syndrome

Alias:
Lymphoproliferative Disorders
Lymphoproliferative Disorder
Combined Immunodeficiency Due to Itk Deficiency
Autosomal Recessive Lymphoproliferative Disease Due to Itk Deficiency
Lymphoproliferative Disorders, Susceptibility to
Itk Deficiency
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Lymphoproliferative Syndrome, also known as lymphoproliferative disorders, is related to autoimmune lymphoproliferative syndrome and ras-associated autoimmune leukoproliferative disorder. An important gene associated with Lymphoproliferative Syndrome is ITK (IL2 Inducible T Cell Kinase), and among its related pathways/superpathways are Innate Immune System and Toll-like receptor signaling pathway. The drugs Tacrolimus and Basiliximab have been mentioned in the context of this disorder. Affiliated tissues include smooth muscle and bone marrow, and related phenotypes are Reduced mammosphere formation and cellular
Related ID:

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
Unknown
<1/1000000
45
491
--

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
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