Lymphangiosarcoma, also known as stewart treves syndrome, is related to conventional angiosarcoma and histiocytoid hemangioma. An important gene associated with Lymphangiosarcoma is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are PAK Pathway and Tyrosine Kinases / Adaptors. The drugs Ifosfamide and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include endothelial and skin, and related phenotypes are homeostasis/metabolism and muscle