Late-Onset Distal Myopathy, Markesbery-Griggs Type, also known as zasp-related myofibrillar myopathy, is related to myopathy and myofibrillar myopathy. An important gene associated with Late-Onset Distal Myopathy, Markesbery-Griggs Type is LDB3 (LIM Domain Binding 3). Affiliated tissues include heart and skeletal muscle, and related phenotypes are progressive proximal muscle weakness and intrinsic hand muscle atrophy