Lethal Congenital Contracture Syndrome (LCCS)

Lethal Congenital Contracture Syndrome, also known as lccs, is related to lethal congenital contracture syndrome 3 and lethal congenital contracture syndrome 4. An important gene associated with Lethal Congenital Contracture Syndrome is GLE1 (GLE1 RNA Export Mediator), and among its related pathways/superpathways are Processing of Capped Intron-Containing Pre-mRNA and HCMV Infection. Affiliated tissues include skeletal muscle and cardiac myocytes, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Decreased influenza A H1N1 (A/WSN/33) virus numbers