Lissencephaly 4 (LIS4)

Alias:

Lissencephaly 4 with Microcephaly

Lis4

Microlissencephaly

Lissencephaly, Type 4

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Lissencephaly 4, also known as lis4, is related to lissencephaly 2 and lissencephaly 1. An important gene associated with Lissencephaly 4 is NDE1 (NudE Neurodevelopment Protein 1), and among its related pathways/superpathways are Cell Cycle Checkpoints and Neurogenesis regulation in the olfactory epithelium. Affiliated tissues include brain and cortex, and related phenotypes are global developmental delay and wide nasal bridge

Related ID：

MALACARDS：LSS010

OMIM：614019

MESH：D054082