Lissencephaly 2 (LIS2)

Alias:

Norman-Roberts Syndrome

Lissencephaly Syndrome, Norman-Roberts Type

Lissencephaly with Cerebellar Hypoplasia

Cobblestone Lissencephaly

Lis2

Lch

Lissencephaly Type 2

Lissencephaly 3

Lissencephaly Syndrome Norman-Roberts Type

Norman-Roberts Lissencephaly Syndrome

Norman Roberts Lissencephaly Syndrome

Lissencephaly Syndrome Type 2

Lissencephaly, Cobblestone

Microlissencephaly Type a

Type Ii Lissencephaly

Lissencephaly, Type 2

Lis3

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Lissencephaly 2, also known as norman-roberts syndrome, is related to lissencephaly 3 and muscular dystrophy-dystroglycanopathy , type a, 4, and has symptoms including ataxia and seizures. An important gene associated with Lissencephaly 2 is RELN (Reelin), and among its related pathways/superpathways are Cell Cycle, Mitotic and Loss of Nlp from mitotic centrosomes. Affiliated tissues include brain and cortex, and related phenotypes are intellectual disability and hypertelorism

Related ID：

MALACARDS：LSS006

OMIM：257320

MESH：C537848