Leishmaniasis

Alias:
Post-Kala-Azar Dermal Leishmaniasis
Post-Kala-Azar Dermal Infectious Disease by Leishmaniasis
Post Kala-Azar Dermal Leishmaniasis
Leishmaniasis, Cutaneous
Leishmaniasis, Visceral
Leishmania Infection
Leishmaniosis
Leishmania
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Leishmaniasis, also known as post-kala-azar dermal leishmaniasis, is related to cutaneous leishmaniasis and visceral leishmaniasis, and has symptoms including exanthema, fever and pruritus. An important gene associated with Leishmaniasis is RN7SL1 (RNA Component Of Signal Recognition Particle 7SL1), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Miltefosine and Paromomycin have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and spleen, and related phenotypes are splenomegaly and hepatomegaly
Related ID:
MESH:D007896
ICD11:1082373067

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
All ages
1-9/1000000
44
575
3

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Mutations
No data available

Related Drugs

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CAS Number
Status
Phase
No data available

Disease Model

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Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
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IF
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