Laryngostenosis

Laryngostenosis, also known as stenosis of larynx, is related to fraser syndrome 1 and epidermolysis bullosa dystrophica. An important gene associated with Laryngostenosis is FREM1 (FRAS1 Related Extracellular Matrix 1), and among its related pathways/superpathways are C-MYB transcription factor network and Development of ureteric collection system. The drugs Curcumin and Ixekizumab have been mentioned in the context of this disorder. Affiliated tissues include trachea and adrenal cortex, and related phenotype is Synthetic lethal with Ras.