Large Cell Medulloblastoma, also known as anaplastic medulloblastoma, is related to medulloblastoma and supratentorial primitive neuroectodermal tumor, and has symptoms including headache, vomiting and gait ataxia. An important gene associated with Large Cell Medulloblastoma is SHH (Sonic Hedgehog Signaling Molecule), and among its related pathways/superpathways are Signaling by Hedgehog and Wnt / Hedgehog / Notch. The drugs Lenograstim and Picropodophyllin have been mentioned in the context of this disorder. Affiliated tissues include brain, and related phenotypes are normal and nervous system