Leptin Deficiency or Dysfunction (LEPD)

Leptin Deficiency or Dysfunction(来自ICD-11)
别称:
Obesity Due to Congenital Leptin Deficiency
Morbid Obesity
Congenital Leptin Deficiency
Lepd
Obesity, Morbid
Obesity, Morbid, Due to Leptin Deficiency
Obesity, Severe, Due to Leptin Deficiency
Leptin Deficiency
Severe Obesity
Morbid Obesity Due to Leptin Deficiency
Obesity, Morbid, Nonsyndromic 1
Leptin Dysfunction
Obesity Morbid
Leptin
加入收藏
Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Leptin Deficiency or Dysfunction, also known as obesity due to congenital leptin deficiency, is related to prader-willi syndrome and metabolic dysfunction-associated steatotic liver disease, and has symptoms including obesity, metabolically benign An important gene associated with Leptin Deficiency or Dysfunction is LEP (Leptin), and among its related pathways/superpathways are GPCR downstream signalling and Signal Transduction. The drugs Clomifene and Octreotide have been mentioned in the context of this disorder. Affiliated tissues include adipocyte and liver, and related phenotypes are obesity and decreased serum leptin
查看原文 参与反馈
相关ID:

基础信息

遗传方式
发病时间
患病率/发病率
相关基因
相关模型
参考文献
MALACARDS
AR
Child
<1/1000000
76
1037
36

疾病表征

#
分类
表征
HPO概率
Orphanet概率
HPO来源
暂无相关数据

基因 & 突变

#
基因
作用分类
分值
突变数量
暂无相关数据

靶点药物

药物名称
CAS号
研发状态
临床阶段
暂无相关数据

疾病模型

类型
名称
MGI
相关基因
品系来源
文献数量
暂无相关数据

文献报道

标题
PMID
期刊
年代
IF
暂无数据
Wechat
Comparison
Al agent
Tutorials
Back to top