Leptin Receptor Deficiency, also known as obesity due to leptin receptor gene deficiency, is related to prader-willi syndrome and morbid obesity and spermatogenic failure. An important gene associated with Leptin Receptor Deficiency is LEPR (Leptin Receptor). The drugs Nadroparin and Octreotide have been mentioned in the context of this disorder. Affiliated tissues include liver and t cells, and related phenotypes are obesity and decreased serum leptin