Leptospirosis, also known as fort bragg fever, is related to adult respiratory distress syndrome and syphilis. An important gene associated with Leptospirosis is PIK3C2A (Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Doxycycline and Amoxicillin have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and kidney, and related phenotypes are nausea and vomiting and hypotension