Leprosy 3 (LPRS3)

Leprosy 3(来自ICD-11)
别称:
Leprosy
Leprosy, Susceptibility to, 3
Infection Due to Mycobacterium Leprae
Leprosy, Susceptibility to
Hansen's Disease
Hansen Disease
Maculoanaesthetic Leprosy
Anaesthesia Leprosy
Anaesthetic Leprosy
Leprosy Unspecified
Leprosy, Type 3
Macular Leprosy
Lprs3
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Leprosy 3, also known as leprosy, is related to borderline leprosy and indeterminate leprosy, and has symptoms including skin lesions, sensory loss and motor loss. An important gene associated with Leprosy 3 is TLR2 (Toll Like Receptor 2), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Clofazimine and Dapsone have been mentioned in the context of this disorder. Affiliated tissues include skin and spinal cord, and related phenotypes are peripheral neuropathy and abnormal autonomic nervous system physiology
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相关ID:
MESH:D007918
ICD11:149072669

基础信息

遗传方式
发病时间
患病率/发病率
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参考文献
MALACARDS
AD
All ages
1-9/100000
66
690
6

疾病表征

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基因 & 突变

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靶点药物

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疾病模型

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MGI
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