Leprosy 3 (LPRS3)

Alias:
Leprosy
Leprosy, Susceptibility to, 3
Infection Due to Mycobacterium Leprae
Leprosy, Susceptibility to
Hansen's Disease
Hansen Disease
Maculoanaesthetic Leprosy
Anaesthesia Leprosy
Anaesthetic Leprosy
Leprosy Unspecified
Leprosy, Type 3
Macular Leprosy
Lprs3
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Leprosy 3, also known as leprosy, is related to borderline leprosy and indeterminate leprosy, and has symptoms including skin lesions, sensory loss and motor loss. An important gene associated with Leprosy 3 is TLR2 (Toll Like Receptor 2), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Clofazimine and Dapsone have been mentioned in the context of this disorder. Affiliated tissues include skin and spinal cord, and related phenotypes are peripheral neuropathy and abnormal autonomic nervous system physiology
Related ID:
MESH:D007918
ICD11:149072669

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
All ages
1-9/100000
66
690
6

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
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