Lung Disease, Immunodeficiency, and Chromosome Breakage Syndrome (LICS)

Lung Disease, Immunodeficiency, and Chromosome Breakage Syndrome, also known as lics, is related to renal cell carcinoma, papillary, 1 and allergic disease. An important gene associated with Lung Disease, Immunodeficiency, and Chromosome Breakage Syndrome is NSMCE3 (NSE3 Homolog, SMC5-SMC6 Complex Component), and among its related pathways/superpathways is 15q11q13 copy number variation. Affiliated tissues include lung and t cells, and related phenotypes are cerebral calcification and failure to thrive in infancy