Long Qt Syndrome 1 (LQT1)

Alias:
Romano-Ward Syndrome
Ward-Romano Syndrome
Lqt1
Rws
Ventricular Fibrillation with Prolonged Qt Interval
Romano-Ward Long Qt Syndrome
Wrs
Long Qt Syndrome 1, Acquired, Susceptibility to
Acquired Susceptibility to Long Qt Syndrome 1
Long Qt Syndrome 1, Acquired
Qt Syndrome, Long, Type 1
Long Qt Syndrome Type 1
Long Qt Syndrome-1
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Long Qt Syndrome 1, also known as romano-ward syndrome, is related to long qt syndrome 2 and long qt syndrome 6, and has symptoms including syncope An important gene associated with Long Qt Syndrome 1 is KCNQ1 (Potassium Voltage-Gated Channel Subfamily Q Member 1), and among its related pathways/superpathways are Activation of cAMP-Dependent PKA and Transmission across Chemical Synapses. The drugs Racepinephrine and Methylphenidate have been mentioned in the context of this disorder. Affiliated tissues include heart and brain, and related phenotypes are prolonged qtc interval and syncope
Related ID:

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AR
AD
All ages
1-5/10000
88
706
278

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
Year
IF
No Data Found!
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