Leiomyosarcoma, also known as leiomyosarcomas, is related to uterus leiomyosarcoma and colon leiomyosarcoma. An important gene associated with Leiomyosarcoma is CHEK2 (Checkpoint Kinase 2), and among its related pathways/superpathways are Signal Transduction and ERK Signaling. The drugs Doxorubicin and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include smooth muscle and uterus, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Decreased substrate adherent cell growth