Leukoencephalopathy with Vanishing White Matter 5 (VWM5)

Leukoencephalopathy with Vanishing White Matter 5, also known as cree leukoencephalopathy, is related to leukoencephalopathy with vanishing white matter and leukoencephalopathy with vanishing white matter 1. An important gene associated with Leukoencephalopathy with Vanishing White Matter 5 is EIF2B5 (Eukaryotic Translation Initiation Factor 2B Subunit Epsilon), and among its related pathways/superpathways are Metabolism of proteins and Apoptotic Pathways in Synovial Fibroblasts. Affiliated tissues include brain, and related phenotypes are progressive neurologic deterioration and megalencephaly