Leukoencephalopathy, Progressive, with Ovarian Failure (LKENP)

Leukoencephalopathy, Progressive, with Ovarian Failure, also known as lkenp, is related to leukodystrophy and leukoencephalopathy with vanishing white matter, and has symptoms including ataxia, muscle spasticity and tremor. An important gene associated with Leukoencephalopathy, Progressive, with Ovarian Failure is AARS2 (Alanyl-TRNA Synthetase 2, Mitochondrial). Affiliated tissues include brain, and related phenotypes are developmental regression and leukoencephalopathy