Leukoencephalopathy, Cystic, Without Megalencephaly, also known as cystic leukoencephalopathy without megalencephaly, is related to rnase t2-deficient leukoencephalopathy and megalencephaly. An important gene associated with Leukoencephalopathy, Cystic, Without Megalencephaly is RNASET2 (Ribonuclease T2), and among its related pathways/superpathways is Pathways of nucleic acid metabolism and innate immune sensing. Affiliated tissues include temporal lobe and brain, and related phenotypes are nystagmus and ataxia