Leukonychia Totalis is related to nail disorder, nonsyndromic congenital, 3 and leukonychia totalis-acanthosis-nigricans-like lesions-abnormal hair syndrome. An important gene associated with Leukonychia Totalis is PLCD1 (Phospholipase C Delta 1). Affiliated tissues include skin, and related phenotypes are abnormal fingernail morphology and nephrolithiasis