Leukemia, Acute Lymphoblastic, also known as acute lymphoblastic leukemia, is related to childhood b-cell acute lymphoblastic leukemia and t-cell acute lymphoblastic leukemia, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Leukemia, Acute Lymphoblastic is PAX5 (Paired Box 5), and among its related pathways/superpathways are Cell differentiation - expanded index and miRNA role in immune response in sepsis. The drugs Nicotine and Vindesine have been mentioned in the context of this disorder. Affiliated tissues include Blood, bone marrow and t cells, and related phenotype is acute lymphoblastic leukemia.