Leukodystrophy, Hypomyelinating, 3 (HLD3)

Leukodystrophy, Hypomyelinating, 3, also known as hypomyelinating leukodystrophy 3, is related to hypomyelinating leukodystrophy and microcephaly, and has symptoms including paraparesis, spastic and abnormal pyramidal signs. An important gene associated with Leukodystrophy, Hypomyelinating, 3 is AIMP1 (Aminoacyl TRNA Synthetase Complex Interacting Multifunctional Protein 1), and among its related pathways/superpathways are tRNA Aminoacylation and p38 MAPK signaling pathway (WikiPathways). Affiliated tissues include brain and peripheral nerve, and related phenotypes are failure to thrive and abnormal pyramidal sign