Legg-Calve-Perthes Disease, also known as perthes disease, is related to synovitis and scheuermann disease. An important gene associated with Legg-Calve-Perthes Disease is COL2A1 (Collagen Type II Alpha 1 Chain), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Diseases of hemostasis. The drugs Benzocaine and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotypes are delayed skeletal maturation and avascular necrosis