Localized Scleroderma

Alias:
Morphea
Localized Fibrosing Scleroderma
Localised Scleroderma
Scleroderma, Circumscribed or Localised
Scleroderma, Circumscribed or Localized
Circumscribed Scleroderma
Scleroderma, Localized
Localised Morphoea
Localised Morphea
Localized Morphea
Favorite
Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Localized Scleroderma, also known as morphea, is related to facial hemiatrophy and scleroderma, familial progressive, and has symptoms including exanthema and pruritus. An important gene associated with Localized Scleroderma is MMP1 (Matrix Metallopeptidase 1), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Lidocaine and Lenograstim have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are thickened skin and arthralgia
Related ID:
MESH:D012594

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
All ages
1-9/100000
25
519
--

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top