Localized Scleroderma, also known as morphea, is related to facial hemiatrophy and scleroderma, familial progressive, and has symptoms including exanthema and pruritus. An important gene associated with Localized Scleroderma is MMP1 (Matrix Metallopeptidase 1), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Lidocaine and Lenograstim have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are thickened skin and arthralgia