Localized Osteosarcoma, also known as localised osteogenic sarcoma, is related to osteogenic sarcoma and childhood osteosarcoma. An important gene associated with Localized Osteosarcoma is FAM87B (Family With Sequence Similarity 87 Member B), and among its related pathways/superpathways are Akt Signaling and TNFR1 Pathway. The drugs Picropodophyllin and Mechlorethamine have been mentioned in the context of this disorder. Affiliated tissues include bone and lung, and related phenotypes are neoplasm and normal