Lichen Sclerosus, also known as ls et a - [lichen sclerosus et atrophicus], is related to phimosis and vulvar dystrophy. An important gene associated with Lichen Sclerosus is ECM1 (Extracellular Matrix Protein 1), and among its related pathways/superpathways are Antiviral mechanism by IFN-stimulated genes and Allograft rejection. The drugs Triamcinolone and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include skin and t cells, and related phenotypes are muscle and respiratory system