Leber Congenital Amaurosis 8 (LCA8)

Leber Congenital Amaurosis 8, also known as lca8, is related to retinitis pigmentosa 12 and retinal disease. An important gene associated with Leber Congenital Amaurosis 8 is CRB1 (Crumbs Cell Polarity Complex Component 1), and among its related pathways/superpathways are Ciliary landscape and Bardet-Biedl syndrome. Affiliated tissues include retina and eye, and related phenotypes are reduced visual acuity and eye poking