Leber Congenital Amaurosis 6, also known as lca6, is related to night blindness and leber plus disease. An important gene associated with Leber Congenital Amaurosis 6 is RPGRIP1 (RPGR Interacting Protein 1), and among its related pathways/superpathways are Ciliary landscape and Bardet-Biedl syndrome. Affiliated tissues include retina and eye, and related phenotypes are cataract and photophobia