Krt1-Related Diffuse Nonepidermolytic Keratoderma, is also known as krt1-related diffuse neppk. An important gene associated with Krt1-Related Diffuse Nonepidermolytic Keratoderma is KRT1 (Keratin 1). Affiliated tissues include skin, and related phenotypes are nonepidermolytic palmoplantar hyperkeratosis and diffuse palmoplantar hyperkeratosis